cellink.pp.normalize

cellink.pp.normalize(adata, *, method='zscore', inplace=True, copy=True)

This function normalizes values using the specified method.

Parameters:

• adata (AnnData) – The annotated data matrix of shape n_obs x n_vars.

• method (str (default: 'zscore')) – The normalization method. Options are: - ‘zscore’: z-score normalization (mean=0, std=1 for each protein). - ‘minmax’: Scale each protein to the range [0, 1]. - ‘median’: Subtract the median of each protein.

• inplace (bool (default: True)) – Whether to update adata or return a copy of the new AnnData object.

• copy (bool (default: True)) – Whether to modify copied input object. Not compatible with inplace=False.

Return type:

AnnData | None

Returns:

Returns the AnnData object with normalized protein abundances or updates the input adata if inplace is True.